Eugene V. Koonin

Sequence - Evolution - Function Eugene V. Koonin Softcover Reprint of the Original 1st Ed. 2003 edition

Marc Notes: Includes bibliographical references and index.; An introduction to the computational approaches that play a critical role in the new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Table of Contents: Preface. Introduction: Personal Interludes. 1. Genomes from Phage to Human. 2. The Evolutionary Concept in Genetics and Genomics. 3. Information Sources for Genomics. 4. Principles and Methods of Sequence Analysis. 5. Genome Annotation and Analysis. 6. Comparative Genomic and New Evolutionary Biology. 7. Evolution of Central Metabolic Pathways: The Playground of Non-orthologous Gene Displacement. 8. Genomes and the Protein Universe. 9. Epilogue: Peering Through the Crystal Ball. Appendices. References. Index.